WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:
Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway       Name:Shigellosis       ID:05131
C=61; O=18; E=1.22; R=14.80; rawP=1.23e-16; adjP=1.91e-14
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000177105 NA RHOG ras homolog family member G 391 ENSG00000177105
2  ENSG00000104312 NA RIPK2 receptor-interacting serine-threonine kinase 2 8767 ENSG00000104312
3  ENSG00000184009 NA ACTG1 actin, gamma 1 71 ENSG00000184009
4  ENSG00000136238 NA RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 5879 ENSG00000136238
5  ENSG00000161638 NA ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 3678 ENSG00000161638
6  ENSG00000241553 NA ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 10093 ENSG00000241553
7  ENSG00000116670 NA MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 10459 ENSG00000116670
8  ENSG00000111229 NA ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 10094 ENSG00000111229
9  ENSG00000097007 NA ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 25 ENSG00000097007
10  ENSG00000130429 NA ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 10095 ENSG00000130429
11  ENSG00000070831 NA CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 998 ENSG00000070831
12  ENSG00000162704 NA ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 10092 ENSG00000162704
13  ENSG00000155849 NA ELMO1 engulfment and cell motility 1 9844 ENSG00000155849
14  ENSG00000108518 NA PFN1 profilin 1 5216 ENSG00000108518
15  ENSG00000109320 NA NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 4790 ENSG00000109320
16  ENSG00000075624 NA ACTB actin, beta 60 ENSG00000075624
17  ENSG00000163466 NA ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 10109 ENSG00000163466
18  ENSG00000173039 NA RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 5970 ENSG00000173039


Database:KEGG pathway       Name:Bacterial invasion of epithelial cells       ID:05100
C=70; O=18; E=1.40; R=12.90; rawP=1.83e-15; adjP=1.42e-13
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000177105 NA RHOG ras homolog family member G 391 ENSG00000177105
2  ENSG00000067560 NA RHOA ras homolog family member A 387 ENSG00000067560
3  ENSG00000184009 NA ACTG1 actin, gamma 1 71 ENSG00000184009
4  ENSG00000145675 NA PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 5295 ENSG00000145675
5  ENSG00000136238 NA RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 5879 ENSG00000136238
6  ENSG00000161638 NA ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 3678 ENSG00000161638
7  ENSG00000241553 NA ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 10093 ENSG00000241553
8  ENSG00000116670 NA MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 10459 ENSG00000116670
9  ENSG00000111229 NA ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 10094 ENSG00000111229
10  ENSG00000160691 NA SHC1 SHC (Src homology 2 domain containing) transforming protein 1 6464 ENSG00000160691
11  ENSG00000130429 NA ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 10095 ENSG00000130429
12  ENSG00000070831 NA CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 998 ENSG00000070831
13  ENSG00000162704 NA ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 10092 ENSG00000162704
14  ENSG00000155849 NA ELMO1 engulfment and cell motility 1 9844 ENSG00000155849
15  ENSG00000122705 NA CLTA clathrin, light chain A 1211 ENSG00000122705
16  ENSG00000075624 NA ACTB actin, beta 60 ENSG00000075624
17  ENSG00000163466 NA ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 10109 ENSG00000163466
18  ENSG00000071205 NA ARHGAP10 Rho GTPase activating protein 10 79658 ENSG00000071205


Database:KEGG pathway       Name:Metabolic pathways       ID:01100
C=1130; O=64; E=22.53; R=2.84; rawP=1.20e-13; adjP=6.20e-12
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000125779 NA PANK2 pantothenate kinase 2 80025 ENSG00000125779
2  ENSG00000093217 NA XYLB xylulokinase homolog (H. influenzae) 9942 ENSG00000093217
3  ENSG00000014919 NA COX15 COX15 homolog, cytochrome c oxidase assembly protein (yeast) 1355 ENSG00000014919
4  ENSG00000101290 NA CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 8760 ENSG00000101290
5  ENSG00000111674 NA ENO2 enolase 2 (gamma, neuronal) 2026 ENSG00000111674
6  ENSG00000198682 NA PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 9060 ENSG00000198682
7  ENSG00000146085 NA MUT methylmalonyl CoA mutase 4594 ENSG00000146085
8  ENSG00000148154 NA UGCG UDP-glucose ceramide glucosyltransferase 7357 ENSG00000148154
9  ENSG00000109814 NA UGDH UDP-glucose 6-dehydrogenase 7358 ENSG00000109814
10  ENSG00000149541 NA B3GAT3 beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) 26229 ENSG00000149541
11  ENSG00000176170 NA SPHK1 sphingosine kinase 1 8877 ENSG00000176170
12  ENSG00000104763 NA ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 427 ENSG00000104763
13  ENSG00000130707 NA ASS1 argininosuccinate synthase 1 445 ENSG00000130707
14  ENSG00000198931 NA APRT adenine phosphoribosyltransferase 353 ENSG00000198931
15  ENSG00000101670 NA LIPG lipase, endothelial 9388 ENSG00000101670
16  ENSG00000131873 NA CHSY1 chondroitin sulfate synthase 1 22856 ENSG00000131873
17  ENSG00000105607 NA GCDH glutaryl-CoA dehydrogenase 2639 ENSG00000105607
18  ENSG00000140650 NA PMM2 phosphomannomutase 2 5373 ENSG00000140650
19  ENSG00000159423 NA ALDH4A1 aldehyde dehydrogenase 4 family, member A1 8659 ENSG00000159423
20  ENSG00000038274 NA MAT2B methionine adenosyltransferase II, beta 27430 ENSG00000038274
21  ENSG00000136908 NA DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 8818 ENSG00000136908
22  ENSG00000117410 NA ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 533 ENSG00000117410
23  ENSG00000025708 NA TYMP thymidine phosphorylase 1890 ENSG00000025708
24  ENSG00000040933 NA INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa 3631 ENSG00000040933
25  ENSG00000184254 NA ALDH1A3 aldehyde dehydrogenase 1 family, member A3 220 ENSG00000184254
26  ENSG00000161267 NA BDH1 3-hydroxybutyrate dehydrogenase, type 1 622 ENSG00000161267
27  ENSG00000243678 NA NME2 NME/NM23 nucleoside diphosphate kinase 2 4831 ENSG00000011052 ENSG00000243678
28  ENSG00000117305 NA HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 3155 ENSG00000117305
29  ENSG00000125458 NA NT5C 5', 3'-nucleotidase, cytosolic 30833 ENSG00000125458
30  ENSG00000090054 NA SPTLC1 serine palmitoyltransferase, long chain base subunit 1 10558 ENSG00000090054
31  ENSG00000074800 NA ENO1 enolase 1, (alpha) 2023 ENSG00000074800
32  ENSG00000069535 NA MAOB monoamine oxidase B 4129 ENSG00000069535
33  ENSG00000153395 NA LPCAT1 lysophosphatidylcholine acyltransferase 1 79888 ENSG00000153395
34  ENSG00000197142 NA ACSL5 acyl-CoA synthetase long-chain family member 5 51703 ENSG00000197142
35  ENSG00000100033 NA PRODH proline dehydrogenase (oxidase) 1 5625 ENSG00000100033
36  ENSG00000111846 NA GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 2651 ENSG00000111846
37  ENSG00000198805 NA PNP purine nucleoside phosphorylase 4860 ENSG00000198805
38  ENSG00000135069 NA PSAT1 phosphoserine aminotransferase 1 29968 ENSG00000135069
39  ENSG00000080819 NA CPOX coproporphyrinogen oxidase 1371 ENSG00000080819
40  ENSG00000116981 NA NT5C1A 5'-nucleotidase, cytosolic IA 84618 ENSG00000116981
41  ENSG00000121039 NA RDH10 retinol dehydrogenase 10 (all-trans) 157506 ENSG00000121039
42  ENSG00000152782 NA PANK1 pantothenate kinase 1 53354 ENSG00000152782
43  ENSG00000166260 NA COX11 COX11 cytochrome c oxidase assembly homolog (yeast) 1353 ENSG00000166260
44  ENSG00000162433 NA AK4 adenylate kinase 4 205 ENSG00000162433
45  ENSG00000158089 NA GALNT14 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14) 79623 ENSG00000158089
46  ENSG00000183010 NA PYCR1 pyrroline-5-carboxylate reductase 1 5831 ENSG00000183010
47  ENSG00000188257 NA PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 5320 ENSG00000188257
48  ENSG00000072042 NA RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 51109 ENSG00000072042
49  ENSG00000035687 NA ADSS adenylosuccinate synthase 159 ENSG00000035687
50  ENSG00000111012 NA CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 1594 ENSG00000111012
51  ENSG00000120697 NA ALG5 asparagine-linked glycosylation 5, dolichyl-phosphate beta-glucosyltransferase homolog (S. cerevisiae) 29880 ENSG00000120697
52  ENSG00000196177 NA ACADSB acyl-CoA dehydrogenase, short/branched chain 36 ENSG00000196177
53  ENSG00000135094 NA SDS serine dehydratase 10993 ENSG00000135094
54  ENSG00000172053 NA QARS glutaminyl-tRNA synthetase 5859 ENSG00000172053
55  ENSG00000101911 NA PRPS2 phosphoribosyl pyrophosphate synthetase 2 5634 ENSG00000101911
56  ENSG00000143753 NA DEGS1 delta(4)-desaturase, sphingolipid 1 8560 ENSG00000143753
57  ENSG00000131473 NA ACLY ATP citrate lyase 47 ENSG00000131473
58  ENSG00000075239 NA ACAT1 acetyl-CoA acetyltransferase 1 38 ENSG00000075239
59  ENSG00000106348 NA IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 3614 ENSG00000106348
60  ENSG00000163882 NA POLR2H polymerase (RNA) II (DNA directed) polypeptide H 5437 ENSG00000163882
61  ENSG00000119523 NA ALG2 asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae) 85365 ENSG00000119523
62  ENSG00000171453 NA POLR1C polymerase (RNA) I polypeptide C, 30kDa 9533 ENSG00000171453
63  ENSG00000008130 NA NADK NAD kinase 65220 ENSG00000008130
64  ENSG00000128928 NA IVD isovaleryl-CoA dehydrogenase 3712 ENSG00000128928


Database:KEGG pathway       Name:Pathogenic Escherichia coli infection       ID:05130
C=56; O=15; E=1.12; R=13.43; rawP=2.11e-13; adjP=8.18e-12
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000097007 NA ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 25 ENSG00000097007
2  ENSG00000067560 NA RHOA ras homolog family member A 387 ENSG00000067560
3  ENSG00000137267 NA TUBB2A tubulin, beta 2A class IIa 7280 ENSG00000137267
4  ENSG00000070831 NA CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 998 ENSG00000070831
5  ENSG00000130429 NA ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 10095 ENSG00000130429
6  ENSG00000184009 NA ACTG1 actin, gamma 1 71 ENSG00000184009
7  ENSG00000162704 NA ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 10092 ENSG00000162704
8  ENSG00000137285 NA TUBB2B tubulin, beta 2B class IIb 347733 ENSG00000137285
9  ENSG00000164924 NA YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 7534 ENSG00000164924
10  ENSG00000075624 NA ACTB actin, beta 60 ENSG00000075624
11  ENSG00000241553 NA ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 10093 ENSG00000241553
12  ENSG00000163466 NA ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 10109 ENSG00000163466
13  ENSG00000196230 NA TUBB tubulin, beta class I 203068 ENSG00000196230
14  ENSG00000111229 NA ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 10094 ENSG00000111229
15  ENSG00000123416 NA TUBA1B tubulin, alpha 1b 10376 ENSG00000123416


Database:KEGG pathway       Name:Neurotrophin signaling pathway       ID:04722
C=127; O=20; E=2.53; R=7.90; rawP=1.08e-12; adjP=3.35e-11
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000067560 NA RHOA ras homolog family member A 387 ENSG00000067560
2  ENSG00000104312 NA RIPK2 receptor-interacting serine-threonine kinase 2 8767 ENSG00000104312
3  ENSG00000146232 NA NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 4794 ENSG00000146232
4  ENSG00000145675 NA PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 5295 ENSG00000145675
5  ENSG00000136238 NA RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 5879 ENSG00000136238
6  ENSG00000141510 NA TP53 tumor protein p53 7157 ENSG00000141510
7  ENSG00000127314 NA RAP1B RAP1B, member of RAS oncogene family 5908 ENSG00000127314
8  ENSG00000064300 NA NGFR nerve growth factor receptor 4804 ENSG00000064300
9  ENSG00000097007 NA ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 25 ENSG00000097007
10  ENSG00000160691 NA SHC1 SHC (Src homology 2 domain containing) transforming protein 1 6464 ENSG00000160691
11  ENSG00000184216 NA IRAK1 interleukin-1 receptor-associated kinase 1 3654 ENSG00000184216
12  ENSG00000070831 NA CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 998 ENSG00000070831
13  ENSG00000163932 NA PRKCD protein kinase C, delta 5580 ENSG00000163932
14  ENSG00000109320 NA NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 4790 ENSG00000109320
15  ENSG00000134070 NA IRAK2 interleukin-1 receptor-associated kinase 2 3656 ENSG00000134070
16  ENSG00000141522 NA ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 396 ENSG00000141522
17  ENSG00000087088 NA BAX BCL2-associated X protein 581 ENSG00000087088
18  ENSG00000164924 NA YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 7534 ENSG00000164924
19  ENSG00000173039 NA RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 5970 ENSG00000173039
20  ENSG00000128245 NA YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 7533 ENSG00000128245


Database:KEGG pathway       Name:Cytokine-cytokine receptor interaction       ID:04060
C=265; O=25; E=5.28; R=4.73; rawP=1.86e-10; adjP=4.27e-09
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000105329 NA TGFB1 transforming growth factor, beta 1 7040 ENSG00000105329
2  ENSG00000108688 NA CCL7 chemokine (C-C motif) ligand 7 6354 ENSG00000108688
3  ENSG00000159110 NA IFNAR2 interferon (alpha, beta and omega) receptor 2 3455 ENSG00000159110
4  ENSG00000159128 NA IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 3460 ENSG00000159128
5  ENSG00000134470 NA IL15RA interleukin 15 receptor, alpha 3601 ENSG00000134470
6  ENSG00000115009 NA CCL20 chemokine (C-C motif) ligand 20 6364 ENSG00000115009
7  ENSG00000126353 NA CCR7 chemokine (C-C motif) receptor 7 1236 ENSG00000126353
8  ENSG00000054967 NA RELT RELT tumor necrosis factor receptor 84957 ENSG00000054967
9  ENSG00000175505 NA CLCF1 cardiotrophin-like cytokine factor 1 23529 ENSG00000175505
10  ENSG00000120889 NA TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 8795 ENSG00000120889
11  ENSG00000131724 NA IL13RA1 interleukin 13 receptor, alpha 1 3597 ENSG00000131724
12  ENSG00000064300 NA NGFR nerve growth factor receptor 4804 ENSG00000064300
13  ENSG00000185291 NA IL3RA interleukin 3 receptor, alpha (low affinity) 3563 ENSG00000185291
14  ENSG00000241839 NA PLEKHO2 pleckstrin homology domain containing, family O member 2 80301 ENSG00000241839 ENSG00000249240
15  ENSG00000115594 NA IL1R1 interleukin 1 receptor, type I 3554 ENSG00000115594
16  ENSG00000111321 NA LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 4055 ENSG00000111321
17  ENSG00000197461 NA PDGFA platelet-derived growth factor alpha polypeptide 5154 ENSG00000197461
18  ENSG00000184371 NA CSF1 colony stimulating factor 1 (macrophage) 1435 ENSG00000184371
19  ENSG00000067182 NA TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 7132 ENSG00000067182
20  ENSG00000177663 NA IL17RA interleukin 17 receptor A 23765 ENSG00000177663
21  ENSG00000145623 NA OSMR oncostatin M receptor 9180 ENSG00000145623
22  ENSG00000019991 NA HGF hepatocyte growth factor (hepapoietin A; scatter factor) 3082 ENSG00000019991
23  ENSG00000077238 NA IL4R interleukin 4 receptor 3566 ENSG00000077238
24  ENSG00000125735 NA TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 8740 ENSG00000125735
25  ENSG00000141655 NA TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 8792 ENSG00000141655


Database:KEGG pathway       Name:Apoptosis       ID:04210
C=87; O=15; E=1.73; R=8.65; rawP=1.93e-10; adjP=4.27e-09
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000115594 NA IL1R1 interleukin 1 receptor, type I 3554 ENSG00000115594
2  ENSG00000184216 NA IRAK1 interleukin-1 receptor-associated kinase 1 3654 ENSG00000184216
3  ENSG00000120889 NA TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 8795 ENSG00000120889
4  ENSG00000134070 NA IRAK2 interleukin-1 receptor-associated kinase 2 3656 ENSG00000134070
5  ENSG00000109320 NA NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 4790 ENSG00000109320
6  ENSG00000145675 NA PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 5295 ENSG00000145675
7  ENSG00000141510 NA TP53 tumor protein p53 7157 ENSG00000141510
8  ENSG00000067182 NA TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 7132 ENSG00000067182
9  ENSG00000087088 NA BAX BCL2-associated X protein 581 ENSG00000087088
10  ENSG00000221823 NA PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 5534 ENSG00000221823
11  ENSG00000137275 NA RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 8737 ENSG00000137275
12  ENSG00000172936 NA MYD88 myeloid differentiation primary response gene (88) 4615 ENSG00000172936
13  ENSG00000173039 NA RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 5970 ENSG00000173039
14  ENSG00000185291 NA IL3RA interleukin 3 receptor, alpha (low affinity) 3563 ENSG00000185291
15  ENSG00000003402 NA CFLAR CASP8 and FADD-like apoptosis regulator 8837 ENSG00000003402


Database:KEGG pathway       Name:Fc gamma R-mediated phagocytosis       ID:04666
C=94; O=15; E=1.87; R=8.00; rawP=5.99e-10; adjP=1.16e-08
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000125753 NA VASP vasodilator-stimulated phosphoprotein 7408 ENSG00000125753
2  ENSG00000070831 NA CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 998 ENSG00000070831
3  ENSG00000130429 NA ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 10095 ENSG00000130429
4  ENSG00000150337 NA FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 2209 ENSG00000150337
5  ENSG00000162704 NA ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 10092 ENSG00000162704
6  ENSG00000163932 NA PRKCD protein kinase C, delta 5580 ENSG00000163932
7  ENSG00000145675 NA PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 5295 ENSG00000145675
8  ENSG00000136238 NA RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 5879 ENSG00000136238
9  ENSG00000176170 NA SPHK1 sphingosine kinase 1 8877 ENSG00000176170
10  ENSG00000175130 NA MARCKSL1 MARCKS-like 1 65108 ENSG00000175130
11  ENSG00000241553 NA ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 10093 ENSG00000241553
12  ENSG00000165527 NA ARF6 ADP-ribosylation factor 6 382 ENSG00000165527
13  ENSG00000163466 NA ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 10109 ENSG00000163466
14  ENSG00000172757 NA CFL1 cofilin 1 (non-muscle) 1072 ENSG00000172757
15  ENSG00000111229 NA ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 10094 ENSG00000111229


Database:KEGG pathway       Name:Focal adhesion       ID:04510
C=200; O=21; E=3.99; R=5.27; rawP=7.51e-10; adjP=1.29e-08
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000067560 NA RHOA ras homolog family member A 387 ENSG00000067560
2  ENSG00000184009 NA ACTG1 actin, gamma 1 71 ENSG00000184009
3  ENSG00000186340 NA THBS2 thrombospondin 2 7058 ENSG00000186340
4  ENSG00000145675 NA PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 5295 ENSG00000145675
5  ENSG00000136238 NA RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 5879 ENSG00000136238
6  ENSG00000127314 NA RAP1B RAP1B, member of RAS oncogene family 5908 ENSG00000127314
7  ENSG00000161638 NA ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 3678 ENSG00000161638
8  ENSG00000041982 NA TNC tenascin C 3371 ENSG00000041982
9  ENSG00000163359 NA COL6A3 collagen, type VI, alpha 3 1293 ENSG00000163359
10  ENSG00000137801 NA THBS1 thrombospondin 1 7057 ENSG00000137801
11  ENSG00000197461 NA PDGFA platelet-derived growth factor alpha polypeptide 5154 ENSG00000197461
12  ENSG00000159840 NA ZYX zyxin 7791 ENSG00000159840
13  ENSG00000125753 NA VASP vasodilator-stimulated phosphoprotein 7408 ENSG00000125753
14  ENSG00000005884 NA ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 3675 ENSG00000005884
15  ENSG00000160691 NA SHC1 SHC (Src homology 2 domain containing) transforming protein 1 6464 ENSG00000160691
16  ENSG00000070831 NA CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 998 ENSG00000070831
17  ENSG00000017427 NA IGF1 insulin-like growth factor 1 (somatomedin C) 3479 ENSG00000017427
18  ENSG00000075624 NA ACTB actin, beta 60 ENSG00000075624
19  ENSG00000019991 NA HGF hepatocyte growth factor (hepapoietin A; scatter factor) 3082 ENSG00000019991
20  ENSG00000171914 NA TLN2 talin 2 83660 ENSG00000171914
21  ENSG00000197565 NA COL4A6 collagen, type IV, alpha 6 1288 ENSG00000197565


Database:KEGG pathway       Name:Purine metabolism       ID:00230
C=162; O=18; E=3.23; R=5.57; rawP=4.94e-09; adjP=7.66e-08
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198682 NA PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 9060 ENSG00000198682
2  ENSG00000198805 NA PNP purine nucleoside phosphorylase 4860 ENSG00000198805
3  ENSG00000116981 NA NT5C1A 5'-nucleotidase, cytosolic IA 84618 ENSG00000116981
4  ENSG00000154678 NA PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 5137 ENSG00000154678
5  ENSG00000137198 NA GMPR guanosine monophosphate reductase 2766 ENSG00000137198
6  ENSG00000162433 NA AK4 adenylate kinase 4 205 ENSG00000162433
7  ENSG00000198931 NA APRT adenine phosphoribosyltransferase 353 ENSG00000198931
8  ENSG00000070019 NA GUCY2C guanylate cyclase 2C (heat stable enterotoxin receptor) 2984 ENSG00000070019
9  ENSG00000035687 NA ADSS adenylosuccinate synthase 159 ENSG00000035687
10  ENSG00000173175 NA ADCY5 adenylate cyclase 5 111 ENSG00000173175
11  ENSG00000101911 NA PRPS2 phosphoribosyl pyrophosphate synthetase 2 5634 ENSG00000101911
12  ENSG00000243678 NA NME2 NME/NM23 nucleoside diphosphate kinase 2 4831 ENSG00000011052 ENSG00000243678
13  ENSG00000138031 NA ADCY3 adenylate cyclase 3 109 ENSG00000138031
14  ENSG00000171302 NA CANT1 calcium activated nucleotidase 1 124583 ENSG00000171302
15  ENSG00000106348 NA IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 3614 ENSG00000106348
16  ENSG00000125458 NA NT5C 5', 3'-nucleotidase, cytosolic 30833 ENSG00000125458
17  ENSG00000163882 NA POLR2H polymerase (RNA) II (DNA directed) polypeptide H 5437 ENSG00000163882
18  ENSG00000171453 NA POLR1C polymerase (RNA) I polypeptide C, 30kDa 9533 ENSG00000171453




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).